Dirk Dormann

Head of Microscopy



















































































































































Deficiency of Cks1 Leads to Learning and Long-Term Memory Defects and p27 Dependent Formation of Neuronal Cofilin Aggregates.

Kukalev A, Ng YM, Ju L, Saidi A, Lane S, Mondragon A, Dormann D, Walker SE, Grey W, Ho PW, Stephens DN, Carr AM, Lamsa K, Tse E, Yu VP.

Cereb Cortex. 2017 Jan 1;27(1):11-23. doi: 10.1093/cercor/bhw354.


Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming.

Cantone I, Bagci H, Dormann D, Dharmalingam G, Nesterova T, Brockdorff N, Rougeulle C, Vallot C, Heard E, Chaligne R, Merkenschlager M, Fisher AG.

Nature Communications 2016 Aug 10;7:12354. doi: 10.1038/ncomms12354.


Reduced Renal Methylarginine Metabolism Protects against Progressive Kidney Damage.

Tomlinson JA, Caplin B, Boruc O, Bruce-Cobbold C, Cutillas P, Dormann D, Faull P, Grossman RC, Khadayate S, Mas VR, Nitsch DD, Wang Z, Norman JT, Wilcox CS, Wheeler DC, Leiper J.

J Am Soc Nephrol. 2015 Dec;26(12):3045-59. doi: 10.1681/ASN.2014030280. Epub 2015 Apr 8.


The brown adipocyte protein CIDEA promotes lipid droplet fusion via a phosphatidic acid-binding amphipathic helix.

Barneda D, Planas-Iglesias J, Gaspar ML, Mohammadyani D, Prasannan S, Dormann D, Han GS, Jesch SA, Carman GM, Kagan V, Parker MG, Ktistakis NT, Klein-Seetharaman J, Dixon AM, Henry SA, Christian M.

Elife. 2015 Nov 26;4:e07485. doi: 10.7554/eLife.07485.


Neuronal control of metabolism through nutrient-dependent modulation of tracheal branching.

Linneweber GA, Jacobson J, Busch KE, Hudry B, Christov CP, Dormann D, Yuan M, Otani T, Knust E, de Bono M, Miguel-Aliaga I.

Cell. 2014 Jan 16;156(1-2):69-83. doi: 10.1016/j.cell.2013.12.008.


ConfocalCheck--a software tool for the automated monitoring of confocal microscope performance.

Hng KI, Dormann D.

PLoS One. 2013 Nov 5;8(11):e79879. doi: 10.1371/journal.pone.0079879. eCollection 2013.


The CDK subunit CKS2 counteracts CKS1 to control cyclin A/CDK2 activity in maintaining replicative fidelity and neurodevelopment.

Frontini M, Kukalev A, Leo E, Ng YM, Cervantes M, Cheng CW, Holic R, Dormann D, Tse E, Pommier Y, Yu V.

Dev Cell. 2012 Aug 14;23(2):356-70. doi: 10.1016/j.devcel.2012.06.018.


The normal mechanisms of pregnancy-induced liver growth are not maintained in mice lacking the bile acid sensor Fxr.

Milona A, Owen BM, van Mil S, Dormann D, Mataki C, Boudjelal M, Cairns W, Schoonjans K, Milligan S, Parker M, White R, Williamson C.

Am J Physiol Gastrointest Liver Physiol. 2010 Feb;298(2):G151-8. doi: 10.1152/ajpgi.00336.2009. Epub 2009 Oct 8.





Cohesin-interacting protein WAPL-1 regulates meiotic chromosome structure and cohesion by antagonizing specific cohesin complexes.

Crawley O1, Barroso C1, Testori S1, Ferrandiz N1, Silva N1, Castellano-Pozo M1, Jaso-Tamame AL1, Martinez-Perez E1.

Elife. 2016 Feb 4;5:e10851. doi: 10.7554/eLife.10851.


Increased axonal bouton dynamics in the aging mouse cortex

Grillo FW, Song S, Teles-Grilo Ruivo LM, Huang L, Gao G, Knott GW, Maco B, Ferretti V, Thompson D, Little GE, De Paola V.

PNAS April 16, 2013 vol. 110 no. 16 E1514-E1523


Temporally controlled modulation of FGF/ERK signaling directs midbrain dopaminergic neural progenitor fate in mouse and human pluripotent stem cells

Jaeger I, Arber C, Risner-Janiczek JR, Kuechler J, Pritzsche D, Chen IC, Naveenan T, Ungless MA, Li M.

Development. 2011 Oct;138(20):4363-74. doi: 10.1242/dev.066746. Epub 2011 Aug 31.


Microspheres as a vehicle for biomolecule delivery to neural stem cells.

Gennet N, Alexander LM, Sánchez-Martín RM, Behrendt JM, Sutherland AJ, Brickman JM, Bradley M, Li M.

N Biotechnol. 2009 Sep;25(6):442-9. doi: 10.1016/j.nbt.2009.05.006. Epub 2009 Jun 11.


Cohesins form chromosomal cis-interactions at the developmentally regulated IFNG locus.

Hadjur S, Williams LM, Ryan NK, Cobb BS, Sexton T, Fraser P, Fisher AG, Merkenschlager M.

Nature. 2009 Jul 16;460(7253):410-3. doi: 10.1038/nature08079. Epub 2009 May 20.





Tumorigenic fragments of APC cause dominant defects in directional cell migration in multiple model systems.

Nelson SA, Li Z, Newton IP, Fraser D, Milne RE, Martin DM, Schiffmann D, Yang X, Dormann D, Weijer CJ, Appleton PL, Näthke IS.

Dis Model Mech. 2012 Nov;5(6):940-7. doi: 10.1242/dmm.008607. Epub 2012 Apr 5.


Imaging cell signalling and movement in development.

Chuai M, Dormann D, Weijer CJ.

Semin Cell Dev Biol. 2009 Oct;20(8):947-55. doi: 10.1016/j.semcdb.2009.09.001. Epub 2009 Sep 9. Review.


Imaging of cell migration.

Dormann D, Weijer CJ.

EMBO J. 2006 Aug 9;25(15):3480-93. Review.


Chemotactic cell movement during Dictyostelium development and gastrulation.

Dormann D, Weijer CJ.

Curr Opin Genet Dev. 2006 Aug;16(4):367-73. Epub 2006 Jun 19. Review.


Visualizing signaling and cell movement during the multicellular stages of dictyostelium development.

Dormann D, Weijer CJ.

Methods Mol Biol. 2006;346:297-309.


Paxillin is required for cell-substrate adhesion, cell sorting and slug migration during Dictyostelium development.

Bukharova T, Weijer G, Bosgraaf L, Dormann D, van Haastert PJ, Weijer CJ.

J Cell Sci. 2005 Sep 15;118(Pt 18):4295-310. Erratum in: J Cell Sci. 2005 Oct 15;118(Pt 20):4913.


In vivo analysis of 3-phosphoinositide dynamics during Dictyostelium phagocytosis and chemotaxis.

Dormann D, Weijer G, Dowler S, Weijer CJ.

J Cell Sci. 2004 Dec 15;117(Pt 26):6497-509. Epub 2004 Nov 30.


Chemotactic cell movement during development.

Dormann D, Weijer CJ.

Curr Opin Genet Dev. 2003 Aug;13(4):358-64. Review.


Becoming Multicellular by Aggregation; The Morphogenesis of the Social Amoebae Dicyostelium discoideum.

Dormann D, Vasiev B, Weijer CJ.

J Biol Phys. 2002 Dec;28(4):765-80. doi: 10.1023/A:1021259326918.


Cell movement patterns during gastrulation in the chick are controlled by positive and negative chemotaxis mediated by FGF4 and FGF8.

Yang X, Dormann D, Münsterberg AE, Weijer CJ.

Dev Cell. 2002 Sep;3(3):425-37.


Simultaneous quantification of cell motility and protein-membrane-association using active contours.

Dormann D, Libotte T, Weijer CJ, Bretschneider T.

Cell Motil Cytoskeleton. 2002 Aug;52(4):221-30.


Visualizing PI3 kinase-mediated cell-cell signaling during Dictyostelium development.

Dormann D, Weijer G, Parent CA, Devreotes PN, Weijer CJ.

Curr Biol. 2002 Jul 23;12(14):1178-88.


Propagating chemoattractant waves coordinate periodic cell movement in Dictyostelium slugs.

Dormann D, Weijer CJ.

Development. 2001 Nov;128(22):4535-43.


A Dictyostelium nuclear phosphatidylinositol phosphate kinase required for developmental gene expression.

Guo K, Nichol R, Skehel P, Dormann D, Weijer CJ, Williams JG, Pears C.

EMBO J. 2001 Nov 1;20(21):6017-27.


cAMP receptor affinity controls wave dynamics, geometry and morphogenesis in Dictyostelium.

Dormann D, Kim JY, Devreotes PN, Weijer CJ.

EJ Cell Sci. 2001 Jul;114(Pt 13):2513-23.


Inducible nuclear translocation of a STAT protein in Dictyostelium prespore cells: implications for morphogenesis and cell-type regulation.

Dormann D, Abe T, Weijer CJ, Williams J.

Development. 2001 Apr;128(7):1081-8.


The control of chemotactic cell movement during Dictyostelium morphogenesis.

Dormann D, Vasiev B, Weijer CJ.

Philos Trans R Soc Lond B Biol Sci. 2000 Jul 29;355(1399):983-91. Review.


Propagating waves control Dictyostelium discoideum morphogenesis.

Dormann D, Vasiev B, Weijer CJ.

Biophys Chem. 1998 May 5;72(1-2):21-35. Review.


Twisted scroll waves organize Dictyostelium mucoroides slugs.

Dormann D, Weijer C, Siegert F.

J Cell Sci. 1997 Aug;110 ( Pt 16):1831-7.


Analysis of cell movement during the culmination phase of Dictyostelium development.

Dormann D, Weijer C, Siegert F.

Development. 1996 Mar;122(3):761-9.